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Question papers>MAHE>2003>Pharmacology

1] Drug used in case of chronic alcoholics to aid their rehabilitation :

  1. Dysulfiram
  2. Sucralfate
  3. Thiamine
  4. Methanol

Ans : A

2] Which is the primary anatomical site of action of hydrochlorthiazide ?

  1. Proximal tubules
  2. Early distal tubules
  3. Late distal tubules
  4. Thick ascending loop of Henles

Ans : B

3] All the following statements regarding insulin is true except

  1. In liver Insulin increases Glycogenisis
  2. Its a polypeptide hormone with A & B chains
  3. Its action is anabolic & increases glucose storage.
  4. It facilitates glucose entry into red blood cells

Ans : D

4] All the following regarding erythromycin are true except :

  1. Its mainly excreted in bile
  2. It binds irreversibly to 50S ribosomal subunits
  3. It is bactericidal
  4. It is contraindicated in patients with hepatic dysfunction

Ans : B

5] DOC for complex partial seizures :

  1. Haloperidol
  2. Imipramine
  3. Alprazolam
  4. Carbamazepine

Ans : D

6] Mechanism of action of Sodium chromoglycate :

  1. Direct bronchodilator effect
  2. Inhibition of release of histamine & other inflammatory mediators
  3. Antimuscarinic effects
  4. Both A & C are correct

Ans : B

7] Antagonist of Warfarin :

  1. Protamine sulfate
  2. Phospholipase
  3. Vitamin-K
  4. Ethacrylate sulfate

Ans : C

8] All these drugs are potentially contraindicated in children except :

  1.  Ciprofloxacin
  2. Chloramphenicol
  3. Tetracycline's
  4. Azithromycin

Ans : D

9] Mechanism of action of Vagabastine

  1. GABA transaminase inhibitor
  2. GABA antagonist
  3. GABA mimetic
  4. GABA uptake inhibitor

Ans : C (KDT pg 706)

10] Drug useful in the medical management of BPH :

  1. Nifidapine
  2. Clonidine
  3. Glycopyrrolate
  4. Finasteride

Ans : D

11] Which drug is coomonly used in M.Gravies ?

  1. Pyridostigmine
  2. Edrophonium hydrochloride
  3. Physostigmine
  4. Steroids

Ans : C

12] Physostigmine is used in the following drug overdosages except :

  1. Edrophonium hydrochloride
  2. Imipramine
  3. Thioridazine
  4. Chlorpromazine

Ans : A

13] Commonest side effects of oral nitrates :

  1. Bradycardia
  2. Headache
  3. Hypotension
  4. Oral ulceration

Ans : B

14] Phenytoin sodium is useful in the treatment of :

  1.  Atrial fibrillation
  2. Digitalis-induced premature ventricular contractions
  3. Paroxysmal SVT
  4. All the above

Ans : D 

 

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